Healthy older men who given large doses of testosterone show increases in muscle mass and power will result nothing in physical function, a new study shows.
This was likely because the men in the current study were "unusually fit for their age," Dr. Thomas W. Storer of Boston University School of Medicine and colleagues say, meaning that the strength and muscle they gained didn't affect their already-excellent physical function.
Future investigations of testosterone therapy should be conducted in people who do have functional limitations, the researchers say, "so that there is room for demonstrable improvement in function with increased muscle strength."
Giving men extra testosterone can build muscle, but studies investigating its effects on performance and function have had mixed results, Storer and his team note in the Journal of the American Geriatrics Society.
This was likely because the men in the current study were "unusually fit for their age," Dr. Thomas W. Storer of Boston University School of Medicine and colleagues say, meaning that the strength and muscle they gained didn't affect their already-excellent physical function.
Future investigations of testosterone therapy should be conducted in people who do have functional limitations, the researchers say, "so that there is room for demonstrable improvement in function with increased muscle strength."
Giving men extra testosterone can build muscle, but studies investigating its effects on performance and function have had mixed results, Storer and his team note in the Journal of the American Geriatrics Society.